The (New) Science of Using Phytosubstances for Wellness

Selected Articles from Aging Sciences, Vince Giuliano's Science & Wellness Blog

} PUBLIC HEALTH, WELLNESS AND AGING

◦  Editorial - Bridging the Great Divide- Health Care vs Wellness

◦  Shift to the wellness-longevity paradigm

◦  Evolution and the prospect for much longer lifespans video blog

◦  Age reversal - video blog

  We are evolving to live longer - video blog

◦  US falling behind in longevity increases - why?

◦  Public health longevity developments - focus on foods

◦  Social evolution and biological evolution - another dialog with Marios Kyriazis

◦  Harnessing the engines of finance and commerce for life-extension

} PLANT-BASED SUBSTANCES AND DISEASE PROCESSES

◦   Plant polyphenols - six epigenetic knockout punches against cancers

◦   Prostate cancer - epigenetic factors, the role of Nrf2, cancer stem cells and actions of phytochemicals

◦   Chronic rhinosinusitis, MRSA, biofilms and manuka honey

   New, emerging and potential treatments for cancers: Part 3 - selected less-known phytochemicals that have long been used in traditional Chinese medicine - focus on gambogic and gambogenic acids

◦   Dietary factors and dementia - Part 1: important recent research

   Dietary factors and dementia - Part 2: possible interventions

   Dietary factors and dementia - Part 3: plant-derived substances that can make a difference

   Curcumin, cancer and longevity

   Neurogenesis, curcumin and longevity

   Diabetes Part 2: Lifestyle, dietary and supplement interventions

} SPECIFIC PHYTOSUBSTANCES

    Adaptogens Part 2: - focus on rhodiola - video blog

    Adaptogens Part 1 - video blog

    Phytosubstances - focus on Andrographis, an old medicine with many possible new applications

    Focus on phytosubstances - amazing properties of epimedium and icariin

    Focus on phytosubstances - Danshen root - amazing properties of salvia miltiorrhiza Bunge

    Phytosubstances - focus on cats claw

    Focus on bitter melon

    Health and longevity benefits of plant polyphenols - focus on grape seed extract

    Focus on ginger

} DIETARY SUPPLEMENTS

    PQQ - activator of PGC-1alpha, SIRT3 and mitochondrial biogenesis

    The many faces of folic acid

    Human growth hormone treatment - a fountain of accelerated aging?

    Klotho, phosphates, cola drinks and longevity

    Valproic acid - The phoenix drug arises again

} AGING AND PUBLIC POLICY

    Improving prospects for extraordinary longevity

    Indefinite life extension - Dialog with Marios Kyriazis

    Gearing up for the war on aging

    If we can multiply lifespans of nematodes by seven, why have we not been able to get anywhere with significant human lifespan extension?

    Aging as a genomic-epigenomic dance

} STRESS MANAGEMENT - HORMESIS

    Multifactorial hormesis - the theory and practice of maintaining health and longevity

    Sarcopenia - the Age-related Los of Muscle Mass and Function - Part I: Pathways and factors

    The Hormetic Wild Animal Zoo and Their Zookeepers

    Mitohormesis

    Radiation hormesis

    Mitochondria Part 2: Mitochondrial Responses to Stress: Mitochondrial Signaling: Survival and Death Pathways

    Hormesis and age retardation

} PHYTOSUBSTANCE-RELATED MOLECULAR HEALTH PATHWAYS

    The pivotal role of Nrf2: Part 1 - a new view on the control of oxidative damage and generation of hormetic effects

    The pivotal role of Nrf2: Part 2 - foods, phyto-substances and other substances that turn on Nrf2

    The pivotal role of Nrf2. Part 3: Part 3 - Is promotion of Nrf2 expression a viable strategy for human human healthspan and lifespan extension?

} HORMESIS AND HEALTH-GENERATING PATHWAYS

      HSP70 to the rescue

      PGC-1alpha and exercise

      New extraordinary longevity lessons from the nematode

} NUTRITION

      Gut microbiota, probiotics, prebiotics and synbiotics - keys to health and longevity

      Mechanisms and Effects of Dietary Restriction

      Alternate-day Fasting - a better alternative

      Nitrates and nitrites - Part 1: bad for you

      Nitrates and nitrites - Part 2: good for you

      Ghrelin hunger, obesity and aging

      Back to blueberries

      Calorie restriction mimetics - focus on avocado extract

} ADVANCED TOPICS IN BIOLOGY

      Observations on the evolution of evolution

      Microtubules, the intra-cellular transport system, health and longevity

                        ◦     Mitochondria in health and aging, and possibilities for life prolongation - Part 1:basic

                        ◦     Mitochondria Part 2: Mitochondrial Responses to Stress: Mitochondrial Signaling: Survival and Death Pathways

                        ◦     End of the free radical theory of aging and negative consequences of indiscriminante antioxidant supplementation

      Quantum biology

      Systems biology and its tools